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I have done some load development for a 338 & I can push a 300 grain Woodleigh solid & RN @ 2400 fps , tell me that woudnt take a buffalo !!.

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The problem is that the diameter of the hole in the lungs gets smaller and you've got to stop some where.
Have seen animals get an awfully long way with a high or single lung shot. Not a great scenario with DG or a park boundary close by.

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