Quote:

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https://en.m.wikipedia.org/wiki/.455_Webley

Quote:

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The .455 cartridge was a service revolver cartridge, featuring a rimmed cartridge firing a .45-caliber bullet at the relatively low velocity of 650 ft/s (190 m/s). The result was a cartridge and handgun combination with comparatively mild recoil. The .455 MK III "cupped" cartridge was rated superior to the .45 Colt in stopping power in the disputed United States Thompson-LaGarde Tests of 1904 that resulted in the adoption by the U.S. of the .45 ACP cartridge.[citation needed]

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With my vast tiger hunting experience I am unsure. . But I think hitting it quickly the first requirement. And a revolver had plenty of follow up shots.

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That's very reminiscent of the handgun for grizzly topic a little while back.
More rounds or bigger rounds and I'd think the same solution would fit both problems.
In the case of the Tiger it's suddenly right their a few feet in front of you, in the case of the bear it's more like a few meters.
You won't shoot a bear in defence with a handgun if you can back away, your only going to be shooting when it charges in close so very similar methods of defence should see some overlap in solutions.

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One shot is all you need.

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