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I loaded with 80gr. of H4350 - that looked to fill the case roughly to the bottom of a 450gr. Hawk bullet.

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A couple of things concerning the 50-110 Win and the 500NE 3".

The 50-110 is WAY down in case capacity compared to the 500 Nitro Express 3".
The 50-110 case is only 2.4" in length compared to 3" for the 500NE.
That's why your 80 grain powder load reached the base of your bullet.
80 grains of H4350 or similar in a 500NE 3" case, would be a long way off the case mouth and would require a fair stack of wadding to fill the gap up to the base of a 440-450 grain bullet.
I just dropped 80 grains of H4350 into a 500NE 3" case and the powder was well over an inch below the case mouth. Approx 1.180" down.

The 500NE 3" has .6" greater case length and approx 20 thou larger base diameter than the 50-110 Win.

The 50-110 drawing shown above in this thread, is marked "NON STANDARD DIMENSIONS" and should not be used as a reference.

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