Quote: I've never hunted Africa or dangerous game animals. But if I was choosing a rifle based on your criteria I would go with .450 3-1/4". I have a single shot in that caliber and I really like the cartridge. I shoot Hornady factory loads out of it with wonderful results and I have no trouble getting the ammo. It does recoil but it feels like a lot less than the recoil of a 470NE. The .450 is the traditional standard to which the other big bores are compared.
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And with the variation of bullet weights available make it an all round choice.