I only have experience with the VXIII series and the Conquest line in lower powers. I like them both, but to my aging eyes the Conquest is clearer and the reticle focus is much easier. The lock ring and screw in eyepeice has never been easy for me. I DO like VXIII and have one of the M77 Magnum I will be hunting buffalo in Zimbabwe with next month. I still like the crystal clear inage of the Zeiss. I have a Zeiss Conquest 2.5-8X32 on the .375 and it works wonderfully. I also have a 3-9x50 on my deer rifle in .30-06 and a 3-9X40 on a .300 magnum. I dont think I have been much help, as I like them both! I feel some brand loyalty to Leupold, but like the performance characteristics of the Zeiss. I have Zeiss binoculars too. Basically I beleive Zeiss is better glass. Hope that helps. BTW, I try to go to a shop that will let me look through both side by side. Thats helped me decide on more than one occasion. Even looking out a window to the outside can give you an idea what they are like IMHO.