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In my opinion, once you start looking over 50 caliber bolt gun there is no easy choice. I can understand selection of the 600 over the two 577's mentioned. The Trex has a large head diameter and will not fit in the affordable CZ550 action. There is a new Montana PH action that will handle the TREX, but I not hear much about those yet. The Nyati might work but it is rebated. The 600ok is rebated too, but with single column feed appears to work well enough. I like the looks of the TREX ammo, good neck length no rebate. Not too practical though, I admit.

There are at least 3 straight case 577's that match the Gibbs bolt face of the CZ550. They have a belt, but no rebate. All skinny enough to fit staggered in the magazine, same as the 505 gibbs. They look like scale up 458Win mags. I like those. I dont have one, I just mean esthetically or for BS on the internet, I like them. If something like that was available off the shelf I'd have one out in a heart beat. Probably loaded down to NE levels. Those three are the result of Ed Hubel effort that started as a 3.25 case 585HE. Then is a 3.0 inch 577BME ( I believe) and a 3rd shorter version. Head & belts may vary slightly among the three. I like the 3.25 version -fondling a sample round as I type. I'd consider cutting down to 3.0 inch, instead of the BME that has no brass. The HE brass might be available. Ed can supply brass too. He posts on this forum regular in the 12Ga from hell thread. The long case can equall or beat any of those mentioned, but beating the TREX or Overkill seems like too much more than too much of too much already. ..ahhh.. A 750 grain bullet is a lot of lead and 585 is a lot of impact area, and deadly at 577NE performance.

Ed has also developed a 700 that fits in the new Montana PH action. FWIW, another option.

There is also a 550mag, based on the Weatherby case that has some appeal. Brass is available and its an easy fit in the CZ550. But here the bullets are the problem. So; while the .550 is a real slick fit in the CZ, the .585 belted like the Hubel fits reasonably well and used legendary and somewhat available although expensive bullets.

I am pretty much at my limit with an 11 lb 505 Gibbs. And where I come at this is 750 grain in 577 would be a big step up and require 13-14 pound rifle for a guy like me. I cannot imagine, moving up from a 458 to 600 all in one step. But thats me, I know there are younger and stronger men who can take that challenge. And the 600 can be loaded light and then worked up.

I would think any 600, with out a brake should be at least 13pounds and even 16-18 would not be excessive.

You might want to consult a recoil calculator and compare where you are now with vs a full house OK in 6.5 pound rifle. I think you really want more weight on that thing.