A 9.3 x 74R will drop a Buffalo, Scrub Bull no problems
if the bullet is put in the right place.

It may not do it with quite the authority of a 375H&H and bigger cals
but I've seen a few drop to the 9.3.

Better to shoot it in the right spot with a good bullet than hit it in the
foot with a Big Bore !!!

500 Nitro