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Huvius, I would think you could achieve full .500NE ballistics in the Ruger chambered for the .50-110. Is there really any difference in the case capacity? I just measured a couple of .500 3" NE cases and found them to be 0.568" at the head. Load up some 570 grain Woodleighs or Hornadys ahead of 100+ grains of IMR4350 and a Fed 215. (My load in the .500 3" is 105 grains of IMR4350). You won't hurt that Ruger, but you might dislocate your shoulder. Just kidding! What does your rifle weigh? Nice rifle, by the way. Curl |