In my 404j with 82 grains of 2209 and CCI mag primer the 400 grain Woodleigh RN produce 2270 fps.
The same load behind the 400 grain Hydro produced 2350 fps and prints 2" lower at 100 yards.

My 9.3 with 286 grain Hydro's print about 4"lower than the 286 grain PP's.

In my fathers 338 win mag the 225 grain Hydro hits 1.5" lower than any of the normal 250 grain loads.

Here is the last two shots I fired before going to Africa.
The top one is a 400 grain Woodleigh RN
The centre one is the Hydro.

This is the 338 win mag before Africa.
The top bullet is the 300 grain RN
The other one is the 225 grain Hydro.