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My first shot on elk was a cow running across, left to right. The 300gr. HP cast bullet hit her in the neck just in front of the shoulder
(I led too far & a little high) but it worked very well indeed. Big veins and clipped the spine.
The 2X scope w/post was not a hindrance to the running shot although a higher powered scope might have been. I suspect up to 4X, NP.

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I completely agree it would not be a hinderance.. again, thought with the close distances, lever guns, etc.. just seems like it would fit there pretty well..