Those are seriously long game shots.

Used to practise out to 300 meters quite regularly with my S&W 4", .44. We had a sheep silhouette on that range's bank, making a good target. I guess the actual range was about 305/6 meters. That's roughly 335 yards. It was a good poke. Elmer told me it was "good practise" with a 44, especially if ever I "need to take care of business and don't have a rifle."
Got that bit of wisdom from him in a phone call when I wore the uniform.

So, long range pracitse can pay off.