Couple guys here swear that the 55gr. Speer Sp. from a .22-250 is the best for black bear.

One co/worker friend shot a good sized black bear with his .22-250, centre-high chest as it faced him, about 100yards away. The bear was standing up on it's hind legs behind a big dead fall tree. This was late fall - mid October and freezing hard at night, but no snow yet, IIRC. He held on the white patch - just in the last couple minutes of light - bang! - bear just disappeared. It was too dark to look him up, so he went back the next morning at day break with another co/worker friend. The bear had just fallen over backwards - DRT - the bullet had centered the white patch and went right through the spine, remains of the bullet were under the hide. Bullet? - 55gr. Speer SP.