Brings back memories - My bro's old Sharps, a shallow rifled barreled action Shilo he bought back in the late 70's, early 80's chambered for the .45 3-1/4" case. 300gr. bullets shot exceptionally well with 62gr. Re#7 for 2,100 or 2,200fps. I think the bullet was a 300gr. Sierra FN (I think but might have been a Hornady) and not a HP. He shot one moose with that load, close 85yard shot and the bullet punched a 5" diameter hole through the lungs, making a 1" exit hole out the far side. There was none of the explosiveness I expected, or shown in Sonny's bear with the RP bullet. The bullet I sectioned showed reasonable jacket thickness compared to the other 300gr. bulelts that looked more like pistol bullets. The next moose collected a 500gr. Hornady RN, driven by 110gr. 2F, then a few more with 460 and 500gr. cast bullets, all of which made 2" diameter tubes of damaged tissue the length of the moose and sacked them within 30 yards of impact. One observation I have made is that the heavy, slow moving bullets traveling lengthwise in the moose made the animals sick, in that they walked slowly after impact, sickly, heads down, whereas light, higher velocity bullets used on broadside shots make them dash as if frightened or stung. This is something I've noticed with modern rifles as well, where the dividing line seems to be in the .30/8mm. area.