My SAKO .375 was my primary deer rifle for years. This type of performance is pretty typical.

I had one failure with the 300 Sierra and ceased using it as a result. In the ole days, stuck with Big Stick 4350, I couldn't get enough of the stuff in the case to allow proper seating of the bullet {dictated also by OAL/magazine length}. Result was, velocity was only 2300 fps. Not super slow, but...

From a rim above, I shot a small knobhead at 270 paces that was feeding on an alfalfa flat below me. I am not certain what the impact velocity was but the deer took off like a racehorse at the shot, and I was able to watch it run hard for at least 200 yards across the field before it disappeared into the adjoining sagebrush.

I called the shot and knew it was good. I eventually found the deer, too, literally tripping over it as it must have died in midstride and must have hit the ground at speed, causing it to slide under the sage and hiding it from my view as I walked.

Bullet took the critter behind the shoulder, and from the angle took one lung high and the other lower.

Both holes were 3/8 inch and looked like they'd been pushed thru slowly with a greased tent stake.

Sometimes the "eating right up to the hole" is not an advantage, especially when the hole is bullet diameter.

Just a warning; some .375 bullets may not open enough when the game is small and the resistance to the bullet slight.