Bramble, I have to correct you here.
No disrespect is meant at all, but i feel I should explane myself here.

I am the man that stated the Cast Performance bullet Company. It was started by me and a man named Joe Gaunt in Gardnerville Nevada, and it was moved to Yerington Nevada in 1992. (to be 100% fair here, I must state that the name "Cast Performance" was Joe's 100%. I names it Carson Valley Cast, which was changed in 92 Joe became the owner of the company when I bowed out, and gave it to him, and it was his Grandfather that funded it, and go it off the ground in a much larger way)

I stayed on a the ballistician and "tec" for several years. I took over the company again in 1999 and was the CEO for that year, until it could be re-organized and "put back into the black"

I tell you this so it's right out front that I am not someone the "read an article" or "thinks they know something".

I have fired thousands of rounds of 45-70 and tens of thousands of rounds of many other calibers in my carrier. I am someone that is on a 2nd barrel in my 375H&H because I shot the throat out of the 1st one, and that rifle was NOT USED FOR MUCH TESTING. That's all from honest shooting in the field!

I don't even know how many thousands of rounds I have fired in a 7mm mauser, but it's a lot. I and on MY 3rd barrel in my 270 Winchester (again, NOT used as a test gun, but all from honest use in the field) I have had to rebarrel three 45 autos, two 44 magnums, one 357, and one 223.
I have put some noteworthy wear on many other rifles and pistols too.

Now with all that said, I will promise you faithfully that a 45-70 with the correct bullet at 1600 FPS will out penitrate a 375 buy a long margin.
I LOVE LOVE LOVE my 375. It's my absolute favorite all around rifle, but I am not going to lie about it. The 45-70 with 460gr and 485 gr bullets would go through about 2X more meat and bone then my best 375 with the best 300 gr solid.

The 375 walks away from the 7mm Mauser and the 270 winchester.
So make no mistake.
The 45-70 is not in any way inferior to the 375 except in flatness of trajectory.

And don't kid yourself about how well it killed either.
In my experience on animals of 500-1000 pounds the 375 seems a bit quicker in putting the game on the ground, but I am talking about seconds only. And very few seconds.
It is not as hard hitting as a 458 or a 460, but it will penitrate as well and sometime even better. It just doesn't make as large a wound channel as a 458 does for the 1st 2 feet of so.

I have not seen many problems with good lever rifles jamming, but I think that if they were 'tested to destruction" the Mauser and the double would last longer, But again, I think you'd have to shoot more than I have to prove it...............

And as i stated above, not many men that I know have shot more rounds than I have. I know there are some, but other than lifetime armoriors in the military, I don't know many. I don’t know ANYONE that’s done more with as many different calibers. There are doubtlessly some, but I have not met them yet.