Daryl_S,
i've shot dozens of whitetails with the Lyman 457122 aka Gould HP (330grs)out of my .451 bullet rifles (PH whitworth, PH volunteer, Rigby style) and it never fails to amaze me how great a killer it is. running shots, standing shots, all angles. the last 4 were 'bag-flops' without the spine being hit. i've never been impressed with a .45 PRB on deer having seen many shot with them. my latest whitetail project bullet is the Lyman 457121 "whitworth" mould modified to drop a 460 grain .4" deep hollow point projectile. it performs like the Gould with more penetration. shot two deer this late ML season with the 457121 HP here in the midwest, absolutely pummeled them. the other kill was with my .69 with prb and 180gr. Swiss 2fg. equal result, bang flop, no spine hit.