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.....The original .404 loading, 400 gr at 2,100 fps and the .450/400 NEs, 400 gr at also 2,100 fps, both have probably killed thousands of buffalo, elephant and other thick skinned game. NO reasons the 10.75x68 with a decent 400 gr at 2,100 fps can't do the same. .....

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Hello NitroX,
Thanks for the reply.

My point exactly ... modern times for a vintage cartridge.