Many if not most .375's put all bullet weights, from 235gr. to 300gr. into about 2 1/2" at 100 yards. Even my .375/06IMP does this.
A cigar box full of ammo should be good ammo if the gun was properly sighted for one of the weights. I found the 235's strike normally, about 1-1/2" higher than the 270's and 300's, in the top half of the "big" group.