160gr 6.5mm bullets at 2800 FPS will get it done.
No problem.
Just make sure your bullet is up to the velocity.

I've gotten fantastic penetration with the Hornady 160RNSN at under 2200fpsMV -- and more launch speed that bullet sheds a lot of it's mass on the way through. Mondo velocity doesn't seem necessary.

That 2800fps number can give you some range if your rifle shoots the long bullets accurately.

Cheers
Tinker