Sectional density.

Sectional density plus velocity at impact is a key determinant of penetration. Bullet construction as a constant. Calibre size and expansion with penetration is the other determinant of killing effectiveness.

But if one looks at the .577? Penetration is important. Velocity with it increases effectiveness. But being hit with something heavy also just seems to work

https://www.vcalc.com/wiki/MichaelBartmess/Sectional+Density

.423, 347 grs. SD is .277
.423, 400 grs, SD is .319
.423, 450 grs, SD is .359

.375, 270 grs, SD is .274
.375, 300 grs, SD is .305
.375, 350 grs, SD is .356

9.3mm, .366, 287 grs, SD is .306
9.3mm, .366, 320 grs, SD is .341

.318 WR, .330, 250 grs, SD is .328
.338, 250 grs, SD is .313

.411, 400 grs, SD is .338

.416, 400 grs, SD is .330
.416, 450 grs, SD is .371

.458, 480 grs, SD is .327
.458, 500 grs, SD is .341

.577, 650 grs, SD is .279
.577, 750 grs, SD is .322
(.577 corrected)

Not wanting to keep going off topic.

The 10.75x63 or x68,
If loaded to 2150 fps or more, 347 gr bullets of decent construction will out perform the lesser .375 cartridges below the magnum (s)

If loaded with a 400 gr to 2100 fps with modern powders and a .404 well designed bullet can do what the .404 Jeffery did in the first half of last century. Buffalo, elephants, lion, rhino etc.

All from my armchair ...

I'd have no problem using them on water buffalo, scrub bull, as well as pigs and sambar iietc.