Daryl, I am using a 160 grain Hornady or a 156 grain PPU bullet on 39 grain of IMR 4350. PPU brass and WW primer.

I also use the same powder charge under the old 160 grain Sierra, but they stopped making them so that is now in the past.
That buck in the picture was killed with a Sierra, but the bullet broke up (I think)and I had 3 exit wounds. One at a 90 degree angle to the direction of the bullet which you can see in the throat at the very front of the neck. On was where I'd expect it to be, in line with the direction of the hit, and one was a bit off the back-side exit and looked for all the world like a 38 caliber pistol wad-cutter hole. Perfectly round and about 3/8" in diameter.

Kinda weird.

I like shooting the PPU 156 in the rifle, but I have never killed anything with one of them. Has anyone reading this used one before on game?
I'd love to know the details of how well they work (or don't work)
Same with the 285 grain PPU 9.3MM. I have never read or spoken to even one man who has killed game with that one either.