I used a Ruger Super Redhawk in 454 Casull, with red dot sight, for my hunt in Eastern Cape. Used it to take a kudu, impala and bushbuck. In the near future I hope to be upgrading to something considerably better made than the Ruger.

I prefer to use a shoulder holster as it's better for a large hunting revolver. Chest holsters seem to be the current fashion with Americans, but they do nothing for me.

Its important to decide whether you want a handgun as a primary hunting weapon, or as a back up for when the rifle isn't in your hands (such as when field dressing game etc). Both uses are valid, but have different considerations. For example: A large magnum calibre revolver or single shot may be your choice as a primary hunting arm whereas a reasonably compact 10mm auto may be better for the back up role.

There are a few websites which specifically cover handgun hunting and may provide a lot more info for those interested.