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These guys always had a booth set up at motorcycle rallies I attended when I had Harley's..

Never had an interest in them, even a little..but, they are built stout..
https://www.bondarms.com/derringers-101/

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Looks good but too large, if a normal finger fits in that trigger guard?

Nice a matching folding knife.

They're not very informative. Are they all .45 Colt/.410?

.45 Colt sounds way too powerful. Buy a decent gun in it. But I suppose it could be loaded back.

Something more effective and larger calibre than a .22 Mag RF, But not sillily powerful. A Derringer which is not petite is not one as far as I am concerned.