So many, where to start, where to start....

Webley hinge-frame with a 4-inch barrel (any historically accurate movie about soldiering for the Empire) or a Bulldog or any short-barreled, big bore in general ("Have you got your revolver, Watson?") Going from the classic end of the spectrum all the way over to the fantasy end, Edward Fox's takedown skeleton rifle from "Day of the Jackal", but in a man's cartridge, not a silly .22 Magnum.

I guess the Webley doesn't qualify, since I said historically accurate, while you specified Hollywood. The two are mutually exclusive.