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Gents, some very good info in the above posts. I will disagree with the 9mm been as effective as the 45 as a stopper if using bullets of the same design. If you are dispatching an animal and brain, neck shooting it then yes, both the same. Shooting in the heart/lung area with rounds that are not fast then the bigger calibre damages more tissue and lets blood out quicker so incapacitates quicker. e.g. ol.

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Yep I agree Greg. From my limited and non recent experience with pigs and pistol cartridges I found that big holes matter. A round through the chest of a pig with a 44, 357/38 or a 9 mm all resulted in a dead pig eventually. But the bigger the hole, preferably 2, entry and exit , usually meant the easier and shorter the track.
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Diameter matters 👍

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That's what she said...

Info for John on some offers from Colt
saw an article this morning they are coming out with a new group of 1911's chambered in .454acp..
https://www.colt.com/category/pistols