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.45ACP worked for me - so did a rifle in .44 Mag. on bears. I never got to shoot a bear with the .44 4", but I'm sure it would have worked a treat. A .45 Colt in a Win. Trapper M94 worked just fine on 2 elk as well.
OR, the 10mm seems to be very effective.. https://www.shootingillustrated.com/articles/2020/10/23/5-reasons-to-choose-a-10-mm-for-self-defense
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