Quite a few Americans have been successful using the 1911 45 ACP (typically using ball ammo) for whitetail deer hunting. Shots would need to be at close range and bullet placement is everything.

May not be legal in some areas. I believe it is illegal in many of the U.S. states to hunt with the 45 ACP or the 1911 (or subsequent versions of the Browning design) type handguns.