One thing that seems to be forgotten in the analysis between various rounds. Same principle as in big bores for dangerous game hunting.

It takes more skill, experience or training to shoot a big bore well. Whether a .45 or a .450.

It is more costly as well.

So the argument goes, it is easier to train the run of the mill shooter with a 9mm or a 5.56.

As a result they will shoot better. The argument is, isn't it better they hit the target with a 9mm or a 5,56 than miss with a .45 or a .450?

Assuming they CAN shoot better, have had adequate training, and CAN hit the target well.

If you DON'T hit the target perfectly, it is FAR better to have a near miss on the kill spot with a .45 or .450 than a 9mm or a 5.56.

And it seems to me, the run of the mill still can't shoot well. And THAT is the real problem. The lack of skill, training and expertise. If that is provided, they COULD use the .45.