I once put three 180gr jacketed split hollowpoint bullets into a raccoon by way of a 1911, at about 5 feet distance, and the little bastard just cruised away down the driveway.
The first shot was center of mass, set him back a foot or two and he just looked up at me with a 'WTF?' kind of expression - the second one got him to step down a stair or two, and the third one finally got him into full retreat mode.

No exit.

Masked bandit made it off my lot, never saw it again - damn Oakland Coons.

Glaser Safety Slugs or shotshells? I don't know.
I think it (as it always seems to) boils down to solid CNS hits and good luck with anything else.

Cheers
Tinker