That .50 S&W ctg. would be fun in a Ruger #1 - easy .50/90 to .50 3 1/4 Sharps ballistics from a 24" barrel.

Guys with handguns - it's a big case - be very careful with reduced 'spl' type loads - Hodgon's IMR Trail Boss may have a definite aplication in this one, for 900fps to 1,000fps range loads.