In custom gunsmithing we have a saying:
Anything can be done--------- if time and price are no object.

So obviously the 425 WR can be made to work in a double. That video is proof.
But the question I have is simply:
Why would you want to?

The 450/400 or 4540 Nitro are already made for doubles. I have nothing bad to say about the performance of the 425WR, but in no way can I say bad things about the 450/400 OR THE 450 NE either.