I'll bite...

Mated with a bead that fills the trough and for the game and at the close ranges typically shot with a rifle of that caliber; you know, big stuff like brontosaurus, tyrannosaurus rex and stegosaurus, all the way down to small game like elephant, rhino, buff and hippo, yes.

On a lighter caliber rifle intended for shooting even-yet-smaller game like chamois, roebuck or whitetail deer out to 100+ meters, no.