I'm a lefty too and was concerned that regulation would be affected by the recoil from the right barrel being constrained by my cheek and from the left not being consrtained by a righty's cheek. I have had no issues but did need to drift sights for about a inch or two horizontal difference from the way the rifle came to me. When it came to me the witness line scribed in the rear sight was in line so the difference was perhaps the difference between a righty and a lefty shooting the same rifle. IIRC, the rifle shot to the right. If my concerns were valid, the rifle ought to have shot to the left. BTW, all loads with all bullets shot to the same (right?) side of POA before I drifted the rear sight.

JPK