I love the .458 bullet,so it would be the 450 Nitro.I can use it on any big game animal here in PA.,and around the world.The biggest animal I want to hunt is the Hippo one on land would be nice.I'd like to take a Cape or two with it,too.I wouldn't be real picky on who made it if I bought one used.Tough to find a 450 used the good selection starts at 500 most of the time.Dave