With my 9.3x74R Chapuis, scoped, I have killed a Kudy at a little over 300 yards. Hit him 3 out of 4 shots.
I killed a coyote at 271 yards, hit him with both shots.

I have shot my 450 No2 and my 450/400 at 200 and 300 yards with the flip up sights.
It just might suprise you how good they shoot at a distance.