I think a Leopard would be tough--

BUT had a local hunter who went to Africa who would disagree-he muffed several shots on a Buff,then got charged by the Buff and finally dropped him at bad breath distance with his 458 Bolt with its 2 pound "hair" trigger with a shotoff his hip!!.The last of 4 rounds got the Buff at his feet.

What did he do then? Sat down and tried to breathe and not throw up.

He doesn't hunt with that big bolt anymore.He gave no comment on wanting a Double.He thinks two shots would not be enough.Guess He would rather be lucky than good any day.