Colorado,
With Lion or Leopard, from what I've read about their speed, if they were coming at full pace from about 40 yards and your first two shots failed to slow them, you would be lucky to get the barrels open to start the reload before they would be all over you!

If you are shooting one of those non ejector doubles that supposedly recoils so damn high that you can just break the gun at top of recoil and let the cases fall out, man you will be lucky to get any more than one shot away before they (lion/leopard) would be on you!

If however, your first two shots from your ejector double were well placed, your animal will be down before he reaches you and you then may have time for a fast reload in case the #ucker tries to get up again!

If you are shooting one of those non ejector doubles that supposedly recoils so damn high that you can just break the gun at top of recoil and let the cases fall out, AND you use the cartridges carried between the fingers of the fore hand to do a reload, and you have a soft in one barrel and a solid in the other, you're most likely in the deep stuff cause while you're checking that you've actually got those cases between your fingers and then deciding what barrel to fire first, you'll most likely forget to put the safety off and ole pussy cat will be on ya 'fore ya can git a shot away and is gunna be doin' a bit of unzipping on yer hide!