Jason van Arde said the bullets used on the cape buffalo were 440 gr Woodleigh SPs. Which are jacketed and designed for this cartridge. I'd be using that if I hunted buffalo with it.

I've got a .500 BPE of some description. If appropriate I'll try that bullet one day if thinking about buffalo. And lead for medium game. The .500 BPs were medium game titles before Nitro Express and cordite arrived.