Is not a .45/90 approaching .450 NE levels? Can you shoot 480 grain projectiles in it?
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The 45-90 .458 2.4 inch case has 96% of the capacity of the .458 Win Mag case and that allows it to be safely loaded to velocities well up into the .458 Win Mag range. Naturally there are other factors involved such as the condition of the rifle and the load components used.
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Yes, it does approach 450 NE levels and 480 grain bullets could be shot in the rifle, but I have not done that.

In my experience, 450 grain .458 North Fork FPS at 2150 fps shoot through ele heads and into the body with frontal brain shots = DRT. THose bullets and Kodiak bullets at 2150 fps shoot through Cape Buff, Bison, Water buff, etc; No need for heavier bullets.

All the above shooting with safe pressures using VV N133.
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My research and the opinion of the bullet designer suggests that the NF 350SS bullets at 2200-2300 fps will be the best all around bullet for my .45-90 rifles, the DR and my 1886. We know what the 1886 can do with these bullets and will soon learn what the DR can do. Planning some exotic game hunts when Texas winter is over.