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There's more case capacity in the 50-110 and that's a heat treated cylinder. The limit will be the brass, and it's Starline brass so really the limit will likely be the shooter.

Frankly, the S&W can be loaded to perform beyond the comfort level of many/most shooters. I don't know how far the owner of that revolver will go with his load development, but there's a great deal of potential there for him to explore.

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Holy crap Tinker!
You'd need to be built like ol' Arnie to hang onto this cannon going flat out with BP!
Imagine the muzzle flash.........it'd be awesome to say the least
Well over my comfort level for sure!