500JRH with 440 grains at 1350fps
475 Linebaugh with 420 grains at 1350fps
With these cartridges you're in the range of 1700-1800 ft/lbs energy.

These are the standard for the 5-shot lightweight revolvers from Freedom Arms or from Huntington and the other custom wheel gun builders.
Finished guns weigh about 3-1/2 pounds.