Here's a little bit of info that may be of interest concerning the 458 Win Mag.

It is often claimed that one of the main reasons that Jack Lott designed the 458 Lott cartridge was because in the late 50's he had been tossed by a Buffalo which had been wounded by him with a 458.
It is usually claimed that the 458 was the culprit and that Jack blamed the cartridge performance, or lack of it, as the reason for the wounding of the Buff as well as the resulting injury when he was tossed.

Well, it aint true!
Sure, Jack was tossed and injured by a wounded bull and he was indeed using a 458 Win, but..........

Jacks two shots were Not well placed.
His first shot, a soft, entered the ribs and went into the gut.
His second, a solid, broke a front leg below the shoulder, went into the gut also, and didn't damage anything vital on the way.
The next 7 shots by the PH from a 375 failed to have any real effect either.
Those 7 shots were supposed to be "well placed".
The PH, Wally Johnson, ended up finishing the bull with a shot to the back of the head from the 458.