500Nitro

The answer is no. The locking mortices in the receiver will peen out of shape in no time depending on how many rounds are put down the tube. I had an older Marlin circa '72 that had this happen to me with around 3000 rounds of Ol' Elmer's load. I thought that it was just getting sour when I decided to convert it to a 475 JDJ which is a 4570 case blown out to 476. The smith at JD Jones' called me and asked me what I had shot in it since the mortices were badly peened and had to me redone before the conversion.