I understand where you're coming from, but I must disagree, hunter angler. A 500gr. .50cal. premium bullet will be better than the slower moving .45 cal. I'm quite sure. How much better, probalby dones't mattermuch, but it will be flatter shooting - ie: lower midrange.

I believe the high SD's bullets were necessary when bullet integrity was lacking, copared to today. Now, lower SD bullets out do the old high SD bullets, sold or soft.

A 500gr. .510cal. bullet has a SD of .27462, while a 400gr. .458 has a SD of .27241. A 550gr. .510" has a SD of .302. That one should make 2,100fps about. will 50gr. weight make any difference if it is solid copper? I doubt it, but do not know.

Those lower numbers are pretty much the same as a 270gr. .375.

Thinking back a couple years to Brian Pierce's trip to Africa and the 2 cape buffalo (bull and cow) he killed with one shot (4 shoulders) with the 400gr. copper solid making 1,750fps - I have to think a 500gr. from the .50 at well over 2,100fps just might be OK & better yet due to a flatter shooting load.