I have two scoped Doubles, a 9.3 and a 450/400. I like them both with scopes as they are both very accurate. I also like them both with the open sights as they handle better. It reduces the range substantially for me though.

I have a nice .303 that I would love to have a scope on but lack the mental toughness to go ahead and do it.

I am not sure that anything bigger than a 400 is a candidate for a scope.