Ripp,

Indeed, very good advice. A .300Wby is certainly more than capable. A .300 paired with a .416 is a great combination, but the .300 can easily be a one gun safari if Buffalo were not included. My hunt will consist of:

Gemsbok
Eland
Kudu
Zebra
Black Wildebeest

Buff - hopeful?

Plus, a stringer of baboons

Regarding the Krieghoff, I don't own one and have never owned a double rifle. My experience comes from shooting for Krieghoff at several Vintage Cup events in the Stopping Rifle category. It took a bit to get used to the cocking device, but I really, really like the way the rifle feels and the way that it mounts. For me, the balance is superb. I'm a big Merkel fan and shoot a 247SL in 12 bore, but their rifles simply do not fit me without some alteration to length of pull and drop at comb/heel.