I've taken moose with the 350 Hornady at 2,260fps muzzle speed. I'd not go higher than this, but anything from about 1,800fps upwards seems to be just fine for that bullet. I used the round nosed bullet, not the newer flat nose. The last batch of round noses I bought had dual cannelures - an interesting feature which should help the bulelt stay together.

Both moose shot resulted in an exit which I prefer. The first took the bullet just over the eye at about 95 yards. The moose was facing me. It wnet lengthwise through that small football shaped brain, throught the heavy bone at the rear of the skull, smashed 3 vertebrae, then exited about 3 feet down the neck from the antlers. I thouth it was excellent performance. The other, a broadside shot was no contest, with a 1" exit hole off side and 4" hole through both lungs. Love that bullet.

If yo've got the gun to take it, the 350gr. Speer only promises to be better, but it must be driven past 1,900fps to expand. It had a jacket that's 1/16" thick.(.062")