Ripp,

If you like a 416 Rigby you will like a 500/416 as well. Its an excellent choice for a (1) carry rifle on safari imo. Though I have never owned one, my father has had several, and he speaks very highly of the cartridge. If you prefer a lighter weight double as he does, this would be a great choice.

It carries moderate pressure ranges as specified here:
39,885 psi (2,750 bar), Copper crusher method
44,962 psi (3,100 bar), Piezzo method

The bullet weight, velocity, and energy is nominal for big game:
Bullet of choice: Woodleigh softnose and solid 410 grains (26.6g)
Velocity: 2,330 ft. sec. (710m/s )
Energy at muzzle:4,940ft. lb. (6,700 J)

JPK is correct that it carries the same characteristics as the 416 Rigby [my favorite bolt chambering], however the 500/416 has a flanged 3 1/4” case for easy extraction. I don't think terming it as a "medium bore cartridge" is accurate though.

I guess it just depends on what you plan to hunt with it, and in what conditions you are hunting. No matter what, it would certainly make a great addition to your fine collection of goodies.