S2 in a 500/416 is all about logic

- not much of a classic look and nostalgic feel there
- very strong (if not the strongest) action so it can handle slightly higher pressures of 500/416 without sweat,
- cock thing makes it very safe to cary and you can get used to with litle practice (same as auto safety)
- hardest thing for me to get used to would be a hood above chambers and I guess it may slow down fast reloading (if there is any practical need for that in the field?) - no ejectors option either
- as you noticed very attractive price for a technicaly improved "tool" and if money wouldn't be a problem no doubt Heym would be the obvious option, however S2 is 1/2 a price!
- same with 500/416 cal. - lacks all the patina but has all the nice physics you can get from .416, balisticaly quite superior to 450/400.
- very accurate

If you can live with that than go for it.

P.S. Before you jump on it, handle one and you will know if thats what you want.