What, powders faster than IMR 4227, like N110 and N120 Vit ?

With two or more powders that can be considered suitible at either extreme of the burning rate for a given cartridge, If velocities are comparable, barrel time is the same, peak pressure is similar.
Can you explain to me why given that total barrel time in a 22 inch barrel is around 9/10000sec, you think that the different Pt curves of either powder take say RL15-H4831 should be significant on the fulcrum stress on the action.

I do not in any event agree with your premis. If you take Data for .470 NE
("Any shot you want" Pg 576) You will note that the faster RL 15 reaches a pressure of 42,900 PSI to generate the same velocity that H4831 does at 36,100psi. An increase of 18% and in fact exceed the MAP for the cartridge.
If you are worried about stress on an action then it just got 18% worse.

Quote "Hey, bullseye will work ! why do ya think Fast burning/pistol powder is used in shotgun shells ???" End Quote

If you believe that you can safely generate 2150 fps with a charge of Bulleye behind a 500 grain head then you are in a distinguished minority.